Gene editing holds great promise for unlocking the full biotechnological potential of microalgae. These photosynthetic microorganisms are capable of producing a wide range of valuable compounds, including lipids, proteins, pigments, and bioactive molecules, making them highly attractive for applications in food, feed, cosmetics, and biofuels. However, natural production levels are often not sufficient for large-scale industrial use. By applying precise gene editing techniques, metabolic pathways can be optimized to enhance the yield and efficiency of target compounds, enabling more sustainable and cost-effective production processes.

In this research, the focus lies on increasing the production of carotenoids, high-value pigments known for their antioxidant properties and applications in health, nutrition, and industry. To achieve this, work is carried out in both well-established and more challenging microalgal systems. On one hand, the model organism Nannochloropsis is used due to its well-characterized genome and the availability of gene editing tools. On the other hand, efforts are directed toward Chlorella, a genus with high industrial relevance but currently limited genetic engineering capabilities.